_guinot-hydrazone-toutes-peaux-at-skinmaze-com-leonilla-comments-preview-1.jpg "Guinot Hydrazone Toutes Peaux at skinmaze.com . Leonilla Comments from hydrazone Video Screenshot Preview 1")
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_mechanisms-124-triple-bond-19.webp "Transformation of a ketone to a hydrazone allows you to reduce it to an alkane. The mechanistic steps to form a hydrazone are very similar to that of imine formation. You can play Carbonyl 18 to review the steps of forming an imine.To start this reaction, hydrazine is a strong nucleophile so it attacks the carbon of the carbonyl, thus breaking the pi bond of the carbonyl.The oxide is then protonated by hydronium and a water molecule is used to transfer a proton from nitrogen to the oxygen wh")
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_mechanisms-124-triple-bond-18.webp "This reaction is known as a Wolff-Kishner reduction where N2 is lost to form an alkane.The first goal is to transfer a proton from the nitrogen to the carbon of the hydrazone.This is done by using hydroxide to deprotonate nitrogen.The negative charge is delocalized through resonance and ends up on the carbon.The lone pair of electrons then accepts the hydrogen to complete the proton transfer.The second step is deprotonation of nitrogen and loss of N2.To do this, hydroxide removes the")
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